WEIGHT LOSS - Is Leptin a miracle cure?

Leptin, when discovered, in the nineties, was regarded by many as the quick-fix for weight loss. Some hoped it would be the miraculous answer to the fat person's prayer, and effect instant weight loss solutions.

However, most were disappointed. Leptin levels were injected into patients, and even when raised tenfold, did not achieve any miraculous change in weight. Some researchers injected it into people who had already lost weight, and monitored their weight maintenance factor. This time it proved successful, and the results of this success in weight control has been documented in the Journal of Clinical Investigation.

These physiological tests - they were not clinical trials, fell short of the anticipated results. Recently, a team researching at Columbia University, has found that injections of Leptin can make the body believe that it does not have to eat more in order to conserve its fat levels.

The body's response to losing weight is age-old. It's a fact that the more body weight is lost the slower is the process of dropping the pounds. The body fights against the process - thought to be a natural protective response, resulting from early man's famine-and-feast eating pattern.

In a small test, the team found that injections of leptin can prevent the natural bodily response that results in the body putting the lost weight back on.

Leptin, a naturally occurring hormone is produced by the fat cells. One of its functions is to keep the brain informed about t the level of fat reserves in the body. A deficiency of Leptin suggests to the brain that fat stores are running low and that they should be replenished - so triggering an eating binge.

So, what do you do about it, naturally, if you are overweight or obese?

However, daily injections do not make for an easy or practical solution to an excess weight problem. The scientists are working at devising a drug that will impede the leptin pathway and give the 'correct' (from the weight loss point of view) info/signals to the brain.

The chemical constituents in Hoodia work within the satiety center by releasing a chemical compound similar to glucose but much stronger. The hypothalamus in the brain interprets this signal to mean that enough food has been consumed, and shuts off all feelings of hunger. Weight loss - Hoodia, the natural appetite suppressant

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